BDBM236526 2-Ethoxy-10-[(2-N,N-dimethylamino-2-methyl)ethyl]benzo[d]isothiazolo[3,2-a]indol-S,S-dioxide (17)

SMILES: CCOc1ccc2C3C(=C(CC(C)N(C)C)c2c1)c1ccccc1S3(=O)=O

InChI Key: InChIKey=MJDLNDHZHBWZQE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236526 (2-Ethoxy-10-[(2-N,N-dimethylamino-2-methyl)ethyl]b...) Show SMILES CCOc1ccc2C3C(=C(CC(C)N(C)C)c2c1)c1ccccc1S3(=O)=O |t:8| Show InChI InChI=1S/C22H25NO3S/c1-5-26-15-10-11-16-18(13-15)19(12-14(2)23(3)4)21-17-8-6-7-9-20(17)27(24,25)22(16)21/h6-11,13-14,22H,5,12H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11.1	-11.3	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
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