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BDBM23657 2-({4,8-diamino-6-[bis(2-hydroxyethyl)amino]pyrimido[5,4-d][1,3]diazin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol::Dipyridamole Analogue, 39

SMILES: Nc1nc(nc2c(N)nc(nc12)N(CCO)CCO)N(CCO)CCO

InChI Key: InChIKey=LFXCKUUYTGMYGM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23657   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (Human))		BDBM23657
PNG
(2-({4,8-diamino-6-[bis(2-hydroxyethyl)amino]pyrimi...)
Show SMILES Nc1nc(nc2c(N)nc(nc12)N(CCO)CCO)N(CCO)CCO
Show InChI InChI=1S/C14H24N8O4/c15-11-10-9(17-13(19-11)21(1-5-23)2-6-24)12(16)20-14(18-10)22(3-7-25)4-8-26/h23-26H,1-8H2,(H2,15,17,19)(H2,16,18,20)
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Similars
Article
PubMed
n/an/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...

J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair