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BDBM23663 2-({6-[(2-hydroxyethyl)amino]-4,8-bis(propylamino)pyrimido[5,4-d][1,3]diazin-2-yl}amino)ethan-1-ol::Dipyridamole Analogue, 45

SMILES: CCCNc1nc(NCCO)nc2c(NCCC)nc(NCCO)nc12

InChI Key: InChIKey=CERSZJHWOHRKOF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23663   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (Human))		BDBM23663
PNG
(2-({6-[(2-hydroxyethyl)amino]-4,8-bis(propylamino)...)
Show SMILES CCCNc1nc(NCCO)nc2c(NCCC)nc(NCCO)nc12
Show InChI InChI=1S/C16H28N8O2/c1-3-5-17-13-11-12(22-15(23-13)19-7-9-25)14(18-6-4-2)24-16(21-11)20-8-10-26/h25-26H,3-10H2,1-2H3,(H2,17,19,22,23)(H2,18,20,21,24)
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Similars
Article
PubMed
n/an/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...

J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair