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BDBM23665 2-({6-[(2-hydroxyethyl)amino]-4,8-bis(propan-2-ylamino)pyrimido[5,4-d][1,3]diazin-2-yl}amino)ethan-1-ol::Dipyridamole Analogue, 47

SMILES: CC(C)Nc1nc(NCCO)nc2c(NC(C)C)nc(NCCO)nc12

InChI Key: InChIKey=YBZQUQINEKFAII-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23665   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (Human))		BDBM23665
PNG
(2-({6-[(2-hydroxyethyl)amino]-4,8-bis(propan-2-yla...)
Show SMILES CC(C)Nc1nc(NCCO)nc2c(NC(C)C)nc(NCCO)nc12
Show InChI InChI=1S/C16H28N8O2/c1-9(2)19-13-11-12(22-15(23-13)17-5-7-25)14(20-10(3)4)24-16(21-11)18-6-8-26/h9-10,25-26H,5-8H2,1-4H3,(H2,17,19,22,23)(H2,18,20,21,24)
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Similars
Article
PubMed
n/an/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...

J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair