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BDBM23669 2-({6-[(2-hydroxyethyl)amino]-4,8-bis[(2-methylpropyl)amino]pyrimido[5,4-d][1,3]diazin-2-yl}amino)ethan-1-ol::Dipyridamole Analogue, 51

SMILES: CC(C)CNc1nc(NCCO)nc2c(NCC(C)C)nc(NCCO)nc12

InChI Key: InChIKey=APZBDYZSAGRHDM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23669   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (Human))		BDBM23669
PNG
(2-({6-[(2-hydroxyethyl)amino]-4,8-bis[(2-methylpro...)
Show SMILES CC(C)CNc1nc(NCCO)nc2c(NCC(C)C)nc(NCCO)nc12
Show InChI InChI=1S/C18H32N8O2/c1-11(2)9-21-15-13-14(24-17(25-15)19-5-7-27)16(22-10-12(3)4)26-18(23-13)20-6-8-28/h11-12,27-28H,5-10H2,1-4H3,(H2,19,21,24,25)(H2,20,22,23,26)
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Similars
Article
PubMed
n/an/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...

J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair