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BDBM23673 2-({6-[(2-hydroxyethyl)amino]-4,8-bis(pentylamino)pyrimido[5,4-d][1,3]diazin-2-yl}amino)ethan-1-ol::Dipyridamole Analogue, 55

SMILES: CCCCCNc1nc(NCCO)nc2c(NCCCCC)nc(NCCO)nc12

InChI Key: InChIKey=ORVRQKILDVDVHJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23673   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (Human))		BDBM23673
PNG
(2-({6-[(2-hydroxyethyl)amino]-4,8-bis(pentylamino)...)
Show SMILES CCCCCNc1nc(NCCO)nc2c(NCCCCC)nc(NCCO)nc12
Show InChI InChI=1S/C20H36N8O2/c1-3-5-7-9-21-17-15-16(26-19(27-17)23-11-13-29)18(22-10-8-6-4-2)28-20(25-15)24-12-14-30/h29-30H,3-14H2,1-2H3,(H2,21,23,26,27)(H2,22,24,25,28)
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Similars
Article
PubMed
n/an/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...

J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair