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BDBM23691 4-[6-(morpholin-4-yl)-4,8-bis(piperidin-1-yl)pyrimido[5,4-d][1,3]diazin-2-yl]morpholine::Dipyridamole Analogue, 73

SMILES: C1CCN(CC1)c1nc(nc2c(nc(nc12)N1CCOCC1)N1CCCCC1)N1CCOCC1

InChI Key: InChIKey=SQSZLYBRYADOGK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23691   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (Human))		BDBM23691
PNG
(4-[6-(morpholin-4-yl)-4,8-bis(piperidin-1-yl)pyrim...)
Show SMILES C1CCN(CC1)c1nc(nc2c(nc(nc12)N1CCOCC1)N1CCCCC1)N1CCOCC1
Show InChI InChI=1S/C24H36N8O2/c1-3-7-29(8-4-1)21-19-20(26-23(27-21)31-11-15-33-16-12-31)22(30-9-5-2-6-10-30)28-24(25-19)32-13-17-34-18-14-32/h1-18H2
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Similars
Article
PubMed
n/an/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...

J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair