null

SMILES: CC(C)c1cccc(NC(=O)c2cccc(c2)N2Cc3cnc4ccnn4c3C2)c1

InChI Key: InChIKey=AXRZBXGIYVXIQQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM236913 (US9388181, 7) Show SMILES CC(C)c1cccc(NC(=O)c2cccc(c2)N2Cc3cnc4ccnn4c3C2)c1 Show InChI InChI=1S/C24H23N5O/c1-16(2)17-5-3-7-20(11-17)27-24(30)18-6-4-8-21(12-18)28-14-19-13-25-23-9-10-26-29(23)22(19)15-28/h3-13,16H,14-15H2,1-2H3,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...				US Patent US9388181 (2016) BindingDB Entry DOI: 10.7270/Q2PZ57QP
					More data for this Ligand-Target Pair