BDBM236915 US9388181, 10

SMILES: O=C(Nc1cccc(c1)N1CCc2c(C1)cnc1ccnn21)c1ccccc1

InChI Key: InChIKey=PNZJAEHEVXWISL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 236915   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM236915 (US9388181, 10) Show SMILES O=C(Nc1cccc(c1)N1CCc2c(C1)cnc1ccnn21)c1ccccc1 Show InChI InChI=1S/C22H19N5O/c28-22(16-5-2-1-3-6-16)25-18-7-4-8-19(13-18)26-12-10-20-17(15-26)14-23-21-9-11-24-27(20)21/h1-9,11,13-14H,10,12,15H2,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	202	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in 1...				US Patent US9388181 (2016) BindingDB Entry DOI: 10.7270/Q2PZ57QP
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM236915 (US9388181, 10) Show SMILES O=C(Nc1cccc(c1)N1CCc2c(C1)cnc1ccnn21)c1ccccc1 Show InChI InChI=1S/C22H19N5O/c28-22(16-5-2-1-3-6-16)25-18-7-4-8-19(13-18)26-12-10-20-17(15-26)14-23-21-9-11-24-27(20)21/h1-9,11,13-14H,10,12,15H2,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	101	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...				US Patent US9388181 (2016) BindingDB Entry DOI: 10.7270/Q2PZ57QP
					More data for this Ligand-Target Pair