BDBM236916 US9388181, 11

SMILES: FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(c1)N1CCc2c(C1)cnc1ccnn21

InChI Key: InChIKey=KZJANSGXJKRYNR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 236916   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM236916 (US9388181, 11) Show SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(c1)N1CCc2c(C1)cnc1ccnn21 Show InChI InChI=1S/C23H18F3N5O/c24-23(25,26)17-4-1-3-15(11-17)22(32)29-18-5-2-6-19(12-18)30-10-8-20-16(14-30)13-27-21-7-9-28-31(20)21/h1-7,9,11-13H,8,10,14H2,(H,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in 1...				US Patent US9388181 (2016) BindingDB Entry DOI: 10.7270/Q2PZ57QP
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM236916 (US9388181, 11) Show SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(c1)N1CCc2c(C1)cnc1ccnn21 Show InChI InChI=1S/C23H18F3N5O/c24-23(25,26)17-4-1-3-15(11-17)22(32)29-18-5-2-6-19(12-18)30-10-8-20-16(14-30)13-27-21-7-9-28-31(20)21/h1-7,9,11-13H,8,10,14H2,(H,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...				US Patent US9388181 (2016) BindingDB Entry DOI: 10.7270/Q2PZ57QP
					More data for this Ligand-Target Pair