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BDBM23695 2-N,2-N,6-N,6-N-tetrakis(2-ethoxyethyl)-4,8-bis(piperidin-1-yl)pyrimido[5,4-d][1,3]diazine-2,6-diamine::Dipyridamole Analogue, 77

SMILES: CCOCCN(CCOCC)c1nc(N2CCCCC2)c2nc(nc(N3CCCCC3)c2n1)N(CCOCC)CCOCC

InChI Key: InChIKey=AOBJTQWTURSZHV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23695   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (Human))		BDBM23695
PNG
(2-N,2-N,6-N,6-N-tetrakis(2-ethoxyethyl)-4,8-bis(pi...)
Show SMILES CCOCCN(CCOCC)c1nc(N2CCCCC2)c2nc(nc(N3CCCCC3)c2n1)N(CCOCC)CCOCC
Show InChI InChI=1S/C32H56N8O4/c1-5-41-23-19-39(20-24-42-6-2)31-33-27-28(29(35-31)37-15-11-9-12-16-37)34-32(36-30(27)38-17-13-10-14-18-38)40(21-25-43-7-3)22-26-44-8-4/h5-26H2,1-4H3
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Similars
Article
PubMed
n/an/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...

J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair