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BDBM23696 4,8-bis(piperidin-1-yl)-2-N,2-N,6-N,6-N-tetrakis(2-propoxyethyl)pyrimido[5,4-d][1,3]diazine-2,6-diamine::Dipyridamole Analogue, 78

SMILES: CCCOCCN(CCOCCC)c1nc(N2CCCCC2)c2nc(nc(N3CCCCC3)c2n1)N(CCOCCC)CCOCCC

InChI Key: InChIKey=GFSNZZMCMKOMMN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23696   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (Human))		BDBM23696
PNG
(4,8-bis(piperidin-1-yl)-2-N,2-N,6-N,6-N-tetrakis(2...)
Show SMILES CCCOCCN(CCOCCC)c1nc(N2CCCCC2)c2nc(nc(N3CCCCC3)c2n1)N(CCOCCC)CCOCCC
Show InChI InChI=1S/C36H64N8O4/c1-5-23-45-27-19-43(20-28-46-24-6-2)35-37-31-32(33(39-35)41-15-11-9-12-16-41)38-36(40-34(31)42-17-13-10-14-18-42)44(21-29-47-25-7-3)22-30-48-26-8-4/h5-30H2,1-4H3
PDB

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Similars
Article
PubMed
n/an/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...

J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair