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SMILES: CC(C)N1CCN(CC1)C(=O)CCCC#Cc1ccn2nc([C@H](C)Nc3ncnc(N)c3C#N)n(-c3ccccc3)c(=O)c12

InChI Key: InChIKey=XSBQOGLHVAKLAL-QHCPKHFHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236963   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM236963 (US9388189, 128) Show SMILES CC(C)N1CCN(CC1)C(=O)CCCC#Cc1ccn2nc([C@H](C)Nc3ncnc(N)c3C#N)n(-c3ccccc3)c(=O)c12 Show InChI InChI=1S/C32H36N10O2/c1-22(2)39-16-18-40(19-17-39)27(43)13-9-4-6-10-24-14-15-41-28(24)32(44)42(25-11-7-5-8-12-25)31(38-41)23(3)37-30-26(20-33)29(34)35-21-36-30/h5,7-8,11-12,14-15,21-23H,4,9,13,16-19H2,1-3H3,(H3,34,35,36,37)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description PI-3 Kinase HTRF kit (ref. #33-037) and the different PI3K recombinant isoforms (ref. #14-602, ref. #14-603, ref. #14-604, ref. #15-558 for Alpha, Be...				US Patent US9388189 (2016) BindingDB Entry DOI: 10.7270/Q2K64H0P
					More data for this Ligand-Target Pair