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BDBM237171 US9403822, 4

SMILES: CC(C)(CNc1ccc(cc1[N+]([O-])=O)S(=O)(=O)NC(=O)c1ccc(cc1Oc1cnc2[nH]ccc2c1)N1CCN(CC2=C(CC(C)(C)CC2)c2ccc(Cl)cc2)CC1)COP(O)(O)=O

InChI Key: InChIKey=JJRJDUKCUYAPQX-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237171   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM237171
PNG
(US9403822, 4)
Show SMILES CC(C)(CNc1ccc(cc1[N+]([O-])=O)S(=O)(=O)NC(=O)c1ccc(cc1Oc1cnc2[nH]ccc2c1)N1CCN(CC2=C(CC(C)(C)CC2)c2ccc(Cl)cc2)CC1)COP(O)(O)=O |t:45|
Show InChI InChI=1S/C44H51ClN7O10PS/c1-43(2)15-13-31(37(24-43)29-5-7-32(45)8-6-29)26-50-17-19-51(20-18-50)33-9-11-36(40(22-33)62-34-21-30-14-16-46-41(30)47-25-34)42(53)49-64(59,60)35-10-12-38(39(23-35)52(54)55)48-27-44(3,4)28-61-63(56,57)58/h5-12,14,16,21-23,25,48H,13,15,17-20,24,26-28H2,1-4H3,(H,46,47)(H,49,53)(H2,56,57,58)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
<0.0100<-15.0n/an/an/an/an/an/a25



ABBVIE INC.

US Patent


Assay Description
Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...

US Patent US9403822 (2016)


BindingDB Entry DOI: 10.7270/Q28P5ZCD
More data for this
Ligand-Target Pair