BDBM237959 US9394285, 40

SMILES: Cc1cc(ccc1-c1cc2c(c[nH]c2cc1Cl)C(O)=O)C1(O)CCC1

InChI Key: InChIKey=JLOXWFOZOYIWFD-UHFFFAOYSA-N

Data: 1 EC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237959   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase Complex 1 (Homo sapiens (Human))	BDBM237959 (US9394285, 40) Show SMILES Cc1cc(ccc1-c1cc2c(c[nH]c2cc1Cl)C(O)=O)C1(O)CCC1 Show InChI InChI=1S/C20H18ClNO3/c1-11-7-12(20(25)5-2-6-20)3-4-13(11)14-8-15-16(19(23)24)10-22-18(15)9-17(14)21/h3-4,7-10,22,25H,2,5-6H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	821	n/a	n/a	7.5	25
Pfizer Inc. US Patent					Assay Description The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...				US Patent US9394285 (2016) BindingDB Entry DOI: 10.7270/Q2DB80Q7
					More data for this Ligand-Target Pair