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SMILES: OC(=O)c1c[nH]c2cc(Cl)c(cc12)-c1ccc2CCOc2c1

InChI Key: InChIKey=RPYKWJHIKXTKHX-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237974   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1


(Homo sapiens (Human))		BDBM237974
PNG
(US9394285, 57)
Show SMILES OC(=O)c1c[nH]c2cc(Cl)c(cc12)-c1ccc2CCOc2c1
Show InChI InChI=1S/C17H12ClNO3/c18-14-7-15-12(13(8-19-15)17(20)21)6-11(14)10-2-1-9-3-4-22-16(9)5-10/h1-2,5-8,19H,3-4H2,(H,20,21)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 64.5n/an/a7.525



Pfizer Inc.

US Patent


Assay Description
The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...

US Patent US9394285 (2016)


BindingDB Entry DOI: 10.7270/Q2DB80Q7
More data for this
Ligand-Target Pair