BDBM238133 US9394289, 29

SMILES: CN(C)C(=O)C1(CCOCC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1

InChI Key: InChIKey=YJDDNHOYXFIQQM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 238133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (c-Fms) (Mus musculus (Mouse))	BDBM238133 (US9394289, 29) Show SMILES CN(C)C(=O)C1(CCOCC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:30| Show InChI InChI=1S/C27H33N5O3/c1-26(2)9-7-18(8-10-26)21-15-19(27(25(34)32(3)4)11-13-35-14-12-27)5-6-22(21)31-24(33)23-29-17-20(16-28)30-23/h5-7,15,17H,8-14H2,1-4H3,(H,29,30)(H,31,33)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.5	25
Janssen Pharmaceutica NV US Patent					Assay Description An autophosphorylation, fluorescence polarization competition immunoassay was used to determine the potency for c-fms inhibition exhibited by selecte...				US Patent US9394289 (2016) BindingDB Entry DOI: 10.7270/Q28K780X
					More data for this Ligand-Target Pair