null
SMILES: COc1cc(NC(C)C)ccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1
InChI Key: InChIKey=IEZFFFOOLULQBR-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor [668-1210,T790M,L858R] (Homo sapiens (Human)) | BDBM238273 (US9409887, I-4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS... | US Patent US9409887 (2016) BindingDB Entry DOI: 10.7270/Q2028QDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [668-1210] (Homo sapiens (Human)) | BDBM238273 (US9409887, I-4) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 65 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS... | US Patent US9409887 (2016) BindingDB Entry DOI: 10.7270/Q2028QDD | |||||||||||
More data for this Ligand-Target Pair |