null

SMILES: CCOC(=O)C(=N\Nc1cccc(c1)-n1nc(C(=O)Nc2ccc(cc2)S(N)(=O)=O)c(C(=O)c2ccccc2)c1-c1ccccc1)\C(=O)c1ccccc1

InChI Key: InChIKey=JMNRPGJWDNPKHW-HJZXASKDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM238303 (Ethyl-2-(2-(3-(4-benzoyl-5-phenyl-3-(4-sulfamoylph...) Show SMILES CCOC(=O)C(=N\Nc1cccc(c1)-n1nc(C(=O)Nc2ccc(cc2)S(N)(=O)=O)c(C(=O)c2ccccc2)c1-c1ccccc1)\C(=O)c1ccccc1 Show InChI InChI=1S/C40H32N6O7S/c1-2-53-40(50)35(38(48)28-17-10-5-11-18-28)44-43-30-19-12-20-31(25-30)46-36(26-13-6-3-7-14-26)33(37(47)27-15-8-4-9-16-27)34(45-46)39(49)42-29-21-23-32(24-22-29)54(41,51)52/h3-25,43H,2H2,1H3,(H,42,49)(H2,41,51,52)/b44-35+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90E+3	-7.55	n/a	n/a	n/a	n/a	n/a	7.4	25
Dumlupinar University					Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...				J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM238303 (Ethyl-2-(2-(3-(4-benzoyl-5-phenyl-3-(4-sulfamoylph...) Show SMILES CCOC(=O)C(=N\Nc1cccc(c1)-n1nc(C(=O)Nc2ccc(cc2)S(N)(=O)=O)c(C(=O)c2ccccc2)c1-c1ccccc1)\C(=O)c1ccccc1 Show InChI InChI=1S/C40H32N6O7S/c1-2-53-40(50)35(38(48)28-17-10-5-11-18-28)44-43-30-19-12-20-31(25-30)46-36(26-13-6-3-7-14-26)33(37(47)27-15-8-4-9-16-27)34(45-46)39(49)42-29-21-23-32(24-22-29)54(41,51)52/h3-25,43H,2H2,1H3,(H,42,49)(H2,41,51,52)/b44-35+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.24E+3	-6.93	n/a	n/a	n/a	n/a	n/a	7.4	25
Dumlupinar University					Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...				J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ
					More data for this Ligand-Target Pair