null

SMILES: COc1ccc2ccc(CC(O)\C=C\[C@H]3CCC(=O)[C@@H]3CCc3ccc(cc3)C(O)=O)cc2c1

InChI Key: InChIKey=ZBKLWSJFQROXNG-ZSYIDUMUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 238329   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM238329 (US9394273, 18) Show SMILES COc1ccc2ccc(CC(O)\C=C\[C@H]3CCC(=O)[C@@H]3CCc3ccc(cc3)C(O)=O)cc2c1 |r| Show InChI InChI=1S/C29H30O5/c1-34-26-13-10-21-6-4-20(16-24(21)18-26)17-25(30)12-9-22-11-15-28(31)27(22)14-5-19-2-7-23(8-3-19)29(32)33/h2-4,6-10,12-13,16,18,22,25,27,30H,5,11,14-15,17H2,1H3,(H,32,33)/b12-9+/t22-,25?,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM238329 (US9394273, 18) Show SMILES COc1ccc2ccc(CC(O)\C=C\[C@H]3CCC(=O)[C@@H]3CCc3ccc(cc3)C(O)=O)cc2c1 |r| Show InChI InChI=1S/C29H30O5/c1-34-26-13-10-21-6-4-20(16-24(21)18-26)17-25(30)12-9-22-11-15-28(31)27(22)14-5-19-2-7-23(8-3-19)29(32)33/h2-4,6-10,12-13,16,18,22,25,27,30H,5,11,14-15,17H2,1H3,(H,32,33)/b12-9+/t22-,25?,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM238329 (US9394273, 18) Show SMILES COc1ccc2ccc(CC(O)\C=C\[C@H]3CCC(=O)[C@@H]3CCc3ccc(cc3)C(O)=O)cc2c1 |r| Show InChI InChI=1S/C29H30O5/c1-34-26-13-10-21-6-4-20(16-24(21)18-26)17-25(30)12-9-22-11-15-28(31)27(22)14-5-19-2-7-23(8-3-19)29(32)33/h2-4,6-10,12-13,16,18,22,25,27,30H,5,11,14-15,17H2,1H3,(H,32,33)/b12-9+/t22-,25?,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2	n/a	n/a	7.4	25
ALLERGAN, INC. US Patent					Assay Description A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair