null

SMILES: COc1cc2CCc3cccc(Oc4ccc(CCc5ccccc5-c1cc2)cc4)c3

InChI Key: InChIKey=UYGWEAIWBIKKSH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 23848   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23848 (25-methoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1^{15...) Show SMILES COc1cc2CCc3cccc(Oc4ccc(CCc5ccccc5-c1cc2)cc4)c3 Show InChI InChI=1S/C29H26O2/c1-30-29-20-23-10-9-22-5-4-7-26(19-22)31-25-16-12-21(13-17-25)11-15-24-6-2-3-8-27(24)28(29)18-14-23/h2-8,12-14,16-20H,9-11,15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM23848 (25-methoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1^{15...) Show SMILES COc1cc2CCc3cccc(Oc4ccc(CCc5ccccc5-c1cc2)cc4)c3 Show InChI InChI=1S/C29H26O2/c1-30-29-20-23-10-9-22-5-4-7-26(19-22)31-25-16-12-21(13-17-25)11-15-24-6-2-3-8-27(24)28(29)18-14-23/h2-8,12-14,16-20H,9-11,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo					Assay Description Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM23848 (25-methoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1^{15...) Show SMILES COc1cc2CCc3cccc(Oc4ccc(CCc5ccccc5-c1cc2)cc4)c3 Show InChI InChI=1S/C29H26O2/c1-30-29-20-23-10-9-22-5-4-7-26(19-22)31-25-16-12-21(13-17-25)11-15-24-6-2-3-8-27(24)28(29)18-14-23/h2-8,12-14,16-20H,9-11,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo					Assay Description Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair