BDBM23920 3-amidinophenylalanine deriv., 62::3-amino-N-(3-{[(2S)-1-[4-(3-aminopropyl)piperidin-1-yl]-3-(3-carbamimidoylphenyl)-1-oxopropan-2-yl]sulfamoyl}phenyl)propanamide

SMILES: NCCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1

InChI Key: InChIKey=FPBMUTVWKLSSHT-DEOSSOPVSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23920   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM23920 (3-amidinophenylalanine deriv., 62 | 3-amino-N-(3-{...) Show SMILES NCCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C27H39N7O4S/c28-12-3-5-19-10-14-34(15-11-19)27(36)24(17-20-4-1-6-21(16-20)26(30)31)33-39(37,38)23-8-2-7-22(18-23)32-25(35)9-13-29/h1-2,4,6-8,16,18-19,24,33H,3,5,9-15,17,28-29H2,(H3,30,31)(H,32,35)/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Chemistry GmbH					Assay Description The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...				J Med Chem 49: 4116-26 (2006) Article DOI: 10.1021/jm051272l BindingDB Entry DOI: 10.7270/Q21C1V64
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM23920 (3-amidinophenylalanine deriv., 62 | 3-amino-N-(3-{...) Show SMILES NCCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C27H39N7O4S/c28-12-3-5-19-10-14-34(15-11-19)27(36)24(17-20-4-1-6-21(16-20)26(30)31)33-39(37,38)23-8-2-7-22(18-23)32-25(35)9-13-29/h1-2,4,6-8,16,18-19,24,33H,3,5,9-15,17,28-29H2,(H3,30,31)(H,32,35)/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Chemistry GmbH					Assay Description The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...				J Med Chem 49: 4116-26 (2006) Article DOI: 10.1021/jm051272l BindingDB Entry DOI: 10.7270/Q21C1V64
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM23920 (3-amidinophenylalanine deriv., 62 | 3-amino-N-(3-{...) Show SMILES NCCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C27H39N7O4S/c28-12-3-5-19-10-14-34(15-11-19)27(36)24(17-20-4-1-6-21(16-20)26(30)31)33-39(37,38)23-8-2-7-22(18-23)32-25(35)9-13-29/h1-2,4,6-8,16,18-19,24,33H,3,5,9-15,17,28-29H2,(H3,30,31)(H,32,35)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Chemistry GmbH					Assay Description The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...				J Med Chem 49: 4116-26 (2006) Article DOI: 10.1021/jm051272l BindingDB Entry DOI: 10.7270/Q21C1V64
					More data for this Ligand-Target Pair
Thrombin (Bos taurus (Bovine))	BDBM23920 (3-amidinophenylalanine deriv., 62 | 3-amino-N-(3-{...) Show SMILES NCCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C27H39N7O4S/c28-12-3-5-19-10-14-34(15-11-19)27(36)24(17-20-4-1-6-21(16-20)26(30)31)33-39(37,38)23-8-2-7-22(18-23)32-25(35)9-13-29/h1-2,4,6-8,16,18-19,24,33H,3,5,9-15,17,28-29H2,(H3,30,31)(H,32,35)/t24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Chemistry GmbH					Assay Description The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...				J Med Chem 49: 4116-26 (2006) Article DOI: 10.1021/jm051272l BindingDB Entry DOI: 10.7270/Q21C1V64
					More data for this Ligand-Target Pair
Factor Xa (fXa) (Bos taurus)	BDBM23920 (3-amidinophenylalanine deriv., 62 | 3-amino-N-(3-{...) Show SMILES NCCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C27H39N7O4S/c28-12-3-5-19-10-14-34(15-11-19)27(36)24(17-20-4-1-6-21(16-20)26(30)31)33-39(37,38)23-8-2-7-22(18-23)32-25(35)9-13-29/h1-2,4,6-8,16,18-19,24,33H,3,5,9-15,17,28-29H2,(H3,30,31)(H,32,35)/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Chemistry GmbH					Assay Description The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...				J Med Chem 49: 4116-26 (2006) Article DOI: 10.1021/jm051272l BindingDB Entry DOI: 10.7270/Q21C1V64
					More data for this Ligand-Target Pair