BDBM239540 US9416126, U24

SMILES: CC(C)N1CCN(CC1)c1cc(ncn1)-c1n[nH]c2ccc(cc12)-c1cn[nH]c1

InChI Key: InChIKey=XLQGVVQXQZUSOC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 239540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM239540 (US9416126, U24) Show SMILES CC(C)N1CCN(CC1)c1cc(ncn1)-c1n[nH]c2ccc(cc12)-c1cn[nH]c1 Show InChI InChI=1S/C21H24N8/c1-14(2)28-5-7-29(8-6-28)20-10-19(22-13-23-20)21-17-9-15(16-11-24-25-12-16)3-4-18(17)26-27-21/h3-4,9-14H,5-8H2,1-2H3,(H,24,25)(H,26,27)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.960	n/a	n/a	n/a	n/a	8.5	25
Merck Sharp & Dohme Corp. US Patent					Assay Description a) 400 nl of a 1:2.15 serial dilution of test compound(98 μM top assay concentration) is spotted via Labcyte Echo to certain wells in a 384 well...				US Patent US9416126 (2016) BindingDB Entry DOI: 10.7270/Q2D50KV9
					More data for this Ligand-Target Pair