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BDBM23974 (3Z)-3-(hydroxyimino)-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride::Tetralone-oxime derivative, 2a

SMILES: ONC1Cc2ccccc2CC1=N

InChI Key: InChIKey=SJWIUIQABFFCKS-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 23974   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytosol aminopeptidase


(Bos taurus (bovine))
BDBM23974
PNG
((3Z)-3-(hydroxyimino)-1,2,3,4-tetrahydronaphthalen...)
Show SMILES ONC1Cc2ccccc2CC1=N
Show InChI InChI=1S/C10H12N2O/c11-9-5-7-3-1-2-4-8(7)6-10(9)12-13/h1-4,10-13H,5-6H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/a8.030



ENSCMu



Assay Description
Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...


Bioorg Med Chem 14: 7241-57 (2006)


Article DOI: 10.1016/j.bmc.2006.06.050
BindingDB Entry DOI: 10.7270/Q2N29V73
More data for this
Ligand-Target Pair
Leukotriene A4 hydrolase


(Homo sapiens (Human))
BDBM23974
PNG
((3Z)-3-(hydroxyimino)-1,2,3,4-tetrahydronaphthalen...)
Show SMILES ONC1Cc2ccccc2CC1=N
Show InChI InChI=1S/C10H12N2O/c11-9-5-7-3-1-2-4-8(7)6-10(9)12-13/h1-4,10-13H,5-6H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



ENSCMu



Assay Description
Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...


Bioorg Med Chem 14: 7241-57 (2006)


Article DOI: 10.1016/j.bmc.2006.06.050
BindingDB Entry DOI: 10.7270/Q2N29V73
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM23974
PNG
((3Z)-3-(hydroxyimino)-1,2,3,4-tetrahydronaphthalen...)
Show SMILES ONC1Cc2ccccc2CC1=N
Show InChI InChI=1S/C10H12N2O/c11-9-5-7-3-1-2-4-8(7)6-10(9)12-13/h1-4,10-13H,5-6H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.80E+6n/an/an/an/an/an/a



ENSCMu



Assay Description
Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...


Bioorg Med Chem 14: 7241-57 (2006)


Article DOI: 10.1016/j.bmc.2006.06.050
BindingDB Entry DOI: 10.7270/Q2N29V73
More data for this
Ligand-Target Pair
Bacterial leucyl aminopeptidase


(Vibrio proteolyticus)
BDBM23974
PNG
((3Z)-3-(hydroxyimino)-1,2,3,4-tetrahydronaphthalen...)
Show SMILES ONC1Cc2ccccc2CC1=N
Show InChI InChI=1S/C10H12N2O/c11-9-5-7-3-1-2-4-8(7)6-10(9)12-13/h1-4,10-13H,5-6H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/a8.030



ENSCMu



Assay Description
Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...


Bioorg Med Chem 14: 7241-57 (2006)


Article DOI: 10.1016/j.bmc.2006.06.050
BindingDB Entry DOI: 10.7270/Q2N29V73
More data for this
Ligand-Target Pair