BDBM239860 US9403767, 9
SMILES: CNC1(CCC(CC1)(N(C)C)c1ccccc1)c1ccccc1
InChI Key: InChIKey=FAOUSJRZQIHJRX-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nociceptin receptor (Homo sapiens (Human)) | BDBM239860 (US9403767, 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 17.8 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The compounds were examined with membranes of recombinant CHO-ORL 1 cells in a receptor binding assay with 3H-nociceptin/orphanin FQ. This test syste... | US Patent US9403767 (2016) BindingDB Entry DOI: 10.7270/Q23R0RSJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM239860 (US9403767, 9) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 640 | -8.44 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
GRUENENTHAL GMBH US Patent | Assay Description The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res... | US Patent US9403767 (2016) BindingDB Entry DOI: 10.7270/Q23R0RSJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM239860 (US9403767, 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.17E+3 | -8.09 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
GRUENENTHAL GMBH US Patent | Assay Description The determination occurred in a homogeneous batch in microtiter plates. For this, dilution series of the respective substances to be tested were incu... | US Patent US9403767 (2016) BindingDB Entry DOI: 10.7270/Q23R0RSJ | |||||||||||
More data for this Ligand-Target Pair |