BDBM23994 5-bromo-5'-phenyl-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3,4]thiadiazole]-2-one::thiadiazole derivative, 9

SMILES: Brc1ccc2NC(=O)C3(NN=C(S3)c3ccccc3)c2c1

InChI Key: InChIKey=RRBYYBWDUNSVAW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23994   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Very long-chain acyl-CoA synthetase (Homo sapiens (Human))	BDBM23994 (5-bromo-5'-phenyl-1,2-dihydro-3'H-spiro[indole-3,2...) Show SMILES Brc1ccc2NC(=O)C3(NN=C(S3)c3ccccc3)c2c1 |c:10| Show InChI InChI=1S/C15H10BrN3OS/c16-10-6-7-12-11(8-10)15(14(20)17-12)19-18-13(21-15)9-4-2-1-3-5-9/h1-8,19H,(H,17,20)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by ChEMBL					Assay Description Inhibition of FATP2 in human HepG2 cells assessed as decrease in fatty acid transport after 5 mins by trypan blue dye based fluorescence quenching me...				Medchemcomm 7: 612-622 (2016) BindingDB Entry DOI: 10.7270/Q2QR502H
					More data for this Ligand-Target Pair
ADAMTS-5 (Aggrecanase-2) (Homo sapiens (Human))	BDBM23994 (5-bromo-5'-phenyl-1,2-dihydro-3'H-spiro[indole-3,2...) Show SMILES Brc1ccc2NC(=O)C3(NN=C(S3)c3ccccc3)c2c1 |c:10| Show InChI InChI=1S/C15H10BrN3OS/c16-10-6-7-12-11(8-10)15(14(20)17-12)19-18-13(21-15)9-4-2-1-3-5-9/h1-8,19H,(H,17,20)	PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description ADAMTS-5 activity was determined using a fluorescence resonance energy transfer (FRET) assay using a QF peptide containing an aggrecanase cleavage si...				Bioorg Med Chem Lett 17: 5630-3 (2007) Article DOI: 10.1016/j.bmcl.2007.07.048 BindingDB Entry DOI: 10.7270/Q2H993G9
					More data for this Ligand-Target Pair