BDBM240098 US9403813, 2

SMILES: Cc1ccc(c(c1)C(=O)N1CC[C@H]1c1nc(no1)-c1cccc(F)c1C)-n1nccn1

InChI Key: InChIKey=YIGGVJZHZCFJLK-IBGZPJMESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240098   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM240098 (US9403813, 2) Show SMILES Cc1ccc(c(c1)C(=O)N1CC[C@H]1c1nc(no1)-c1cccc(F)c1C)-n1nccn1 Show InChI InChI=1S/C22H19FN6O2/c1-13-6-7-18(29-24-9-10-25-29)16(12-13)22(30)28-11-8-19(28)21-26-20(27-31-21)15-4-3-5-17(23)14(15)2/h3-7,9-10,12,19H,8,11H2,1-2H3/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9403813 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RS2
					More data for this Ligand-Target Pair
Orexin receptor type 1 (Homo sapiens (Human))	BDBM240098 (US9403813, 2) Show SMILES Cc1ccc(c(c1)C(=O)N1CC[C@H]1c1nc(no1)-c1cccc(F)c1C)-n1nccn1 Show InChI InChI=1S/C22H19FN6O2/c1-13-6-7-18(29-24-9-10-25-29)16(12-13)22(30)28-11-8-19(28)21-26-20(27-31-21)15-4-3-5-17(23)14(15)2/h3-7,9-10,12,19H,8,11H2,1-2H3/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	713	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9403813 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RS2
					More data for this Ligand-Target Pair