BDBM240740 US9422263, 24

SMILES: FC(F)C1=C(C#N)C(C(C#N)=C(N1)C(F)F)c1ccc2[nH]ncc2c1

InChI Key: InChIKey=IJMNXEGVGVTCEE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 240740   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM240740 (US9422263, 24) Show SMILES FC(F)C1=C(C#N)C(C(C#N)=C(N1)C(F)F)c1ccc2[nH]ncc2c1 |c:3,10| Show InChI InChI=1S/C16H9F4N5/c17-15(18)13-9(4-21)12(10(5-22)14(24-13)16(19)20)7-1-2-11-8(3-7)6-23-25-11/h1-3,6,12,15-16,24H,(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	7.0	32
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9422263 (2016) BindingDB Entry DOI: 10.7270/Q2JQ0ZW2
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