BDBM240758 US9422307, 42

SMILES: Nc1nc(Nc2ccc(nc2)N2CCOCC2)nc2c(csc12)-c1cnc2ccccc2c1

InChI Key: InChIKey=LWLKLYWYERSFEK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 240758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM240758 (US9422307, 42) Show SMILES Nc1nc(Nc2ccc(nc2)N2CCOCC2)nc2c(csc12)-c1cnc2ccccc2c1 Show InChI InChI=1S/C24H21N7OS/c25-23-22-21(18(14-33-22)16-11-15-3-1-2-4-19(15)26-12-16)29-24(30-23)28-17-5-6-20(27-13-17)31-7-9-32-10-8-31/h1-6,11-14H,7-10H2,(H3,25,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	7.5	25
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY US Patent					Assay Description Full sequence FAK was purchased from Cell Signaling (Catalog No.: 7796). ULight-poly GT (PerkinElmer #TRF0100-D), Eu-anti-phospho-Tyr (PT66) (PerkinE...				US Patent US9422307 (2016) BindingDB Entry DOI: 10.7270/Q29885XC
					More data for this Ligand-Target Pair