BDBM240763 US9422307, 47

SMILES: C[C@@H](Nc1nc(NCCN2CCOCC2)nc2c(C=C)csc12)c1ccccc1

InChI Key: InChIKey=FIADULCZQIMHJH-MRXNPFEDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 240763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM240763 (US9422307, 47) Show SMILES C[C@@H](Nc1nc(NCCN2CCOCC2)nc2c(C=C)csc12)c1ccccc1 |r| Show InChI InChI=1S/C22H27N5OS/c1-3-17-15-29-20-19(17)25-22(23-9-10-27-11-13-28-14-12-27)26-21(20)24-16(2)18-7-5-4-6-8-18/h3-8,15-16H,1,9-14H2,2H3,(H2,23,24,25,26)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	7.5	25
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY US Patent					Assay Description Full sequence FAK was purchased from Cell Signaling (Catalog No.: 7796). ULight-poly GT (PerkinElmer #TRF0100-D), Eu-anti-phospho-Tyr (PT66) (PerkinE...				US Patent US9422307 (2016) BindingDB Entry DOI: 10.7270/Q29885XC
					More data for this Ligand-Target Pair