BDBM240829 (2R,3S)-3-amino-2-hydroxy-N-((S)-1-(hydroxyamino)-1-oxo-3-phenylpropan-2-yl)-3-phenylpropanamide hydrochloride (7f)

SMILES: N[C@H]([C@@H](O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NO)c1ccccc1

InChI Key: InChIKey=NRIWMIVTLWLPDM-HRCADAONSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240829   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gelatinase 2 (MMP-2) (Sus scrofa (Pig))	BDBM240829 ((2R,3S)-3-amino-2-hydroxy-N-((S)-1-(hydroxyamino)-...) Show SMILES N[C@H]([C@@H](O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NO)c1ccccc1 |r| Show InChI InChI=1S/C18H21N3O4/c19-15(13-9-5-2-6-10-13)16(22)18(24)20-14(17(23)21-25)11-12-7-3-1-4-8-12/h1-10,14-16,22,25H,11,19H2,(H,20,24)(H,21,23)/t14-,15-,16+/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.49E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shan Dong University					Assay Description Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...				J Enzyme Inhib Med Chem 28: 545-51 (2013) Article DOI: 10.3109/14756366.2012.656622 BindingDB Entry DOI: 10.7270/Q24J0D1S
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM240829 ((2R,3S)-3-amino-2-hydroxy-N-((S)-1-(hydroxyamino)-...) Show SMILES N[C@H]([C@@H](O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NO)c1ccccc1 |r| Show InChI InChI=1S/C18H21N3O4/c19-15(13-9-5-2-6-10-13)16(22)18(24)20-14(17(23)21-25)11-12-7-3-1-4-8-12/h1-10,14-16,22,25H,11,19H2,(H,20,24)(H,21,23)/t14-,15-,16+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	7.5	25
Shan Dong University					Assay Description IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...				J Enzyme Inhib Med Chem 28: 545-51 (2013) Article DOI: 10.3109/14756366.2012.656622 BindingDB Entry DOI: 10.7270/Q24J0D1S
					More data for this Ligand-Target Pair