BDBM240844 US9394331, 136::US9394331, 48

SMILES: OCC1OC(n2ccc(=O)[nH]c2=O)[C@@]2(CCO2)[C@@H]1O

InChI Key:

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 240844   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA polymerase (NS5B) (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM240844 (US9394331, 136 | US9394331, 48) Show SMILES OCC1OC(n2ccc(=O)[nH]c2=O)[C@@]2(CCO2)[C@@H]1O |r| Show InChI	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	7.5	27
Gilead Pharmasset LLC US Patent					Assay Description The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...				US Patent US9394331 (2016) BindingDB Entry DOI: 10.7270/Q2W094TH
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (NS5B) (S282T) (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM240844 (US9394331, 136 | US9394331, 48) Show SMILES OCC1OC(n2ccc(=O)[nH]c2=O)[C@@]2(CCO2)[C@@H]1O |r| Show InChI	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	27
Gilead Pharmasset LLC US Patent					Assay Description The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...				US Patent US9394331 (2016) BindingDB Entry DOI: 10.7270/Q2W094TH
					More data for this Ligand-Target Pair
RNA polymerase (NS5B) (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM240844 (US9394331, 136 | US9394331, 48) Show SMILES OCC1OC(n2ccc(=O)[nH]c2=O)[C@@]2(CCO2)[C@@H]1O |r| Show InChI	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.94E+4	n/a	n/a	7.5	27
Gilead Pharmasset LLC US Patent					Assay Description The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...				US Patent US9394331 (2016) BindingDB Entry DOI: 10.7270/Q2W094TH
					More data for this Ligand-Target Pair