BDBM240845 US9394331, 140::US9394331, 52

SMILES: Nc1ccn(C2OC(CO)[C@@H](O)[C@]22CCO2)c(=O)n1

InChI Key: InChIKey=IAWVRYQPXVENTD-YGHADEAESA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 240845   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA polymerase (NS5B) (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM240845 (US9394331, 140 | US9394331, 52) Show SMILES Nc1ccn(C2OC(CO)[C@@H](O)[C@]22CCO2)c(=O)n1 |r| Show InChI InChI=1S/C11H15N3O5/c12-7-1-3-14(10(17)13-7)9-11(2-4-18-11)8(16)6(5-15)19-9/h1,3,6,8-9,15-16H,2,4-5H2,(H2,12,13,17)/t6?,8-,9?,11-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>5.45E+4	n/a	n/a	7.5	27
Gilead Pharmasset LLC US Patent					Assay Description The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...				US Patent US9394331 (2016) BindingDB Entry DOI: 10.7270/Q2W094TH
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (NS5B) (S282T) (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM240845 (US9394331, 140 | US9394331, 52) Show SMILES Nc1ccn(C2OC(CO)[C@@H](O)[C@]22CCO2)c(=O)n1 |r| Show InChI InChI=1S/C11H15N3O5/c12-7-1-3-14(10(17)13-7)9-11(2-4-18-11)8(16)6(5-15)19-9/h1,3,6,8-9,15-16H,2,4-5H2,(H2,12,13,17)/t6?,8-,9?,11-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.67E+4	n/a	n/a	n/a	n/a	7.5	27
Gilead Pharmasset LLC US Patent					Assay Description The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...				US Patent US9394331 (2016) BindingDB Entry DOI: 10.7270/Q2W094TH
					More data for this Ligand-Target Pair
RNA polymerase (NS5B) (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM240845 (US9394331, 140 | US9394331, 52) Show SMILES Nc1ccn(C2OC(CO)[C@@H](O)[C@]22CCO2)c(=O)n1 |r| Show InChI InChI=1S/C11H15N3O5/c12-7-1-3-14(10(17)13-7)9-11(2-4-18-11)8(16)6(5-15)19-9/h1,3,6,8-9,15-16H,2,4-5H2,(H2,12,13,17)/t6?,8-,9?,11-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>8.48E+3	n/a	n/a	7.5	27
Gilead Pharmasset LLC US Patent					Assay Description The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...				US Patent US9394331 (2016) BindingDB Entry DOI: 10.7270/Q2W094TH
					More data for this Ligand-Target Pair