null

SMILES: COC(=O)NC(C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(nc1)-c1cc(F)c(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C

InChI Key: InChIKey=CUWXAZIRPXQUMT-QSWWHUPUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 241855   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [1973-2419] (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM241855 (US9416139, 33) Show SMILES COC(=O)NC(C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(nc1)-c1cc(F)c(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C51H58FN9O7/c1-27(2)42(57-49(65)67-5)47(63)60-19-9-11-39(60)44-54-26-38(56-44)30-14-15-36(53-25-30)31-22-35(52)41(34-24-51(23-33(31)34)17-7-8-18-51)29-13-16-37-32(21-29)46(62)59-45(55-37)40-12-10-20-61(40)48(64)43(28(3)4)58-50(66)68-6/h13-16,21-22,25-28,39-40,42-43H,7-12,17-20,23-24H2,1-6H3,(H,57,65)(H,58,66)/b36-31-,38-30+,41-29-/t39-,40-,42?,43-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0220	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241855 (US9416139, 33) Show SMILES COC(=O)NC(C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(nc1)-c1cc(F)c(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C51H58FN9O7/c1-27(2)42(57-49(65)67-5)47(63)60-19-9-11-39(60)44-54-26-38(56-44)30-14-15-36(53-25-30)31-22-35(52)41(34-24-51(23-33(31)34)17-7-8-18-51)29-13-16-37-32(21-29)46(62)59-45(55-37)40-12-10-20-61(40)48(64)43(28(3)4)58-50(66)68-6/h13-16,21-22,25-28,39-40,42-43H,7-12,17-20,23-24H2,1-6H3,(H,57,65)(H,58,66)/b36-31-,38-30+,41-29-/t39-,40-,42?,43-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0780	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair