BDBM241879 US9416154, 22

SMILES: CCOC(=O)[C@H](C)NP(=O)(OC(C)[C@H]1O[C@@H](n2ccc3c(N)ncnc23)[C@](C)(F)[C@@H]1O)Oc1ccccc1Cl

InChI Key: InChIKey=LJLXSLFKZQRQGK-XMCCYAIVSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 241879   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM241879 (US9416154, 22) Show SMILES CCOC(=O)[C@H](C)NP(=O)(OC(C)[C@H]1O[C@@H](n2ccc3c(N)ncnc23)[C@](C)(F)[C@@H]1O)Oc1ccccc1Cl |r| Show InChI InChI=1S/C24H30ClFN5O7P/c1-5-35-22(33)13(2)30-39(34,38-17-9-7-6-8-16(17)25)37-14(3)18-19(32)24(4,26)23(36-18)31-11-10-15-20(27)28-12-29-21(15)31/h6-14,18-19,23,32H,5H2,1-4H3,(H,30,34)(H2,27,28,29)/t13-,14?,18+,19+,23+,24+,39?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	7.3	25
Merck Sharp & Dohme Corp. US Patent					Assay Description The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...				US Patent US9416154 (2016) BindingDB Entry DOI: 10.7270/Q2KK99PV
					More data for this Ligand-Target Pair