BDBM241881 US9416154, 32

SMILES: CC(C)OC(=O)[C@H](C)NP(=O)(Oc1cccc2ccccc12)OC(C)(C)[C@H]1O[C@@H](n2ccc3c(N)ncnc23)[C@](C)(F)[C@@H]1O

InChI Key: InChIKey=BKXPIBZOEWZFFL-NQYIIHRFSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 241881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM241881 (US9416154, 32) Show SMILES CC(C)OC(=O)[C@H](C)NP(=O)(Oc1cccc2ccccc12)OC(C)(C)[C@H]1O[C@@H](n2ccc3c(N)ncnc23)[C@](C)(F)[C@@H]1O |r| Show InChI InChI=1S/C30H37FN5O7P/c1-17(2)40-27(38)18(3)35-44(39,42-22-13-9-11-19-10-7-8-12-20(19)22)43-29(4,5)24-23(37)30(6,31)28(41-24)36-15-14-21-25(32)33-16-34-26(21)36/h7-18,23-24,28,37H,1-6H3,(H,35,39)(H2,32,33,34)/t18-,23+,24-,28+,30+,44?/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	7.3	25
Merck Sharp & Dohme Corp. US Patent					Assay Description The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...				US Patent US9416154 (2016) BindingDB Entry DOI: 10.7270/Q2KK99PV
					More data for this Ligand-Target Pair