null

SMILES: COC(=O)[C@H](C)NP(=O)(O[C@H](C)[C@H]1O[C@@H](n2ccc3c(N)ncnc23)[C@](C)(O)[C@@H]1O)Oc1ccccc1

InChI Key: InChIKey=OUQIZOSWJPXRQI-FOUZMDNWSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 241886   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM241886 (US9416154, 34) Show SMILES COC(=O)[C@H](C)NP(=O)(O[C@H](C)[C@H]1O[C@@H](n2ccc3c(N)ncnc23)[C@](C)(O)[C@@H]1O)Oc1ccccc1 |r| Show InChI InChI=1S/C23H30N5O8P/c1-13(21(30)33-4)27-37(32,36-15-8-6-5-7-9-15)35-14(2)17-18(29)23(3,31)22(34-17)28-11-10-16-19(24)25-12-26-20(16)28/h5-14,17-18,22,29,31H,1-4H3,(H,27,32)(H2,24,25,26)/t13-,14+,17+,18+,22+,23+,37?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	7.3	25
Merck Sharp & Dohme Corp. US Patent					Assay Description The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...				US Patent US9416154 (2016) BindingDB Entry DOI: 10.7270/Q2KK99PV
					More data for this Ligand-Target Pair