BDBM241986 4-{5-[5-(4-Bromophenyl)-1,2-oxazol-3-yl]-1,3,4-thiadiazol-2-yl}benzene-1,3-diol (10)
SMILES: Oc1ccc(-c2nnc(s2)-c2cc(on2)-c2ccc(Br)cc2)c(O)c1
InChI Key: InChIKey=JFWOAGVTSXOONX-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM241986 (4-{5-[5-(4-Bromophenyl)-1,2-oxazol-3-yl]-1,3,4-thi...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.93E+5 | n/a | n/a | n/a | n/a | 8.0 | 2 |
University of Life Sciences | Assay Description Seven different concentrations of the synthesized compounds in the range 10^−3-10^−9 M were measured at 412 nm. All the assays were under... | J Enzyme Inhib Med Chem 28: 816-23 (2013) Article DOI: 10.3109/14756366.2012.688041 BindingDB Entry DOI: 10.7270/Q2WW7GJ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM241986 (4-{5-[5-(4-Bromophenyl)-1,2-oxazol-3-yl]-1,3,4-thi...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.52E+4 | n/a | n/a | n/a | n/a | 8.0 | 2 |
University of Life Sciences | Assay Description Seven different concentrations of the synthesized compounds in the range 10^−3-10^−9 M were measured at 412 nm. All the assays were under... | J Enzyme Inhib Med Chem 28: 816-23 (2013) Article DOI: 10.3109/14756366.2012.688041 BindingDB Entry DOI: 10.7270/Q2WW7GJ8 | |||||||||||
More data for this Ligand-Target Pair |