null

SMILES: CC(=O)OCC(=O)NC1CCN(CCc2ccc(Oc3nc4ccccc4s3)cc2)CC1

InChI Key: InChIKey=UNNDDWDUVLBXRL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24230   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM24230 (Benzthiazole compound, 27o | [(1-{2-[4-(1,3-benzot...) Show SMILES CC(=O)OCC(=O)NC1CCN(CCc2ccc(Oc3nc4ccccc4s3)cc2)CC1 Show InChI InChI=1S/C24H27N3O4S/c1-17(28)30-16-23(29)25-19-11-14-27(15-12-19)13-10-18-6-8-20(9-7-18)31-24-26-21-4-2-3-5-22(21)32-24/h2-9,19H,10-16H2,1H3,(H,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel.				J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24230 (Benzthiazole compound, 27o | [(1-{2-[4-(1,3-benzot...) Show SMILES CC(=O)OCC(=O)NC1CCN(CCc2ccc(Oc3nc4ccccc4s3)cc2)CC1 Show InChI InChI=1S/C24H27N3O4S/c1-17(28)30-16-23(29)25-19-11-14-27(15-12-19)13-10-18-6-8-20(9-7-18)31-24-26-21-4-2-3-5-22(21)32-24/h2-9,19H,10-16H2,1H3,(H,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	25
Johnson & Johnson Pharmaceutical					Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,...				J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX
					More data for this Ligand-Target Pair