null

SMILES: CC(=O)NC1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1

InChI Key: InChIKey=UVZMEOGKJYOCNE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM24236 (Benzthiazole compound, 33n | N-(1-{[4-(1,3-benzoth...) Show SMILES CC(=O)NC1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1 Show InChI InChI=1S/C21H23N3O2S/c1-15(25)22-17-10-12-24(13-11-17)14-16-6-8-18(9-7-16)26-21-23-19-4-2-3-5-20(19)27-21/h2-9,17H,10-14H2,1H3,(H,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel.				J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24236 (Benzthiazole compound, 33n | N-(1-{[4-(1,3-benzoth...) Show SMILES CC(=O)NC1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1 Show InChI InChI=1S/C21H23N3O2S/c1-15(25)22-17-10-12-24(13-11-17)14-16-6-8-18(9-7-16)26-21-23-19-4-2-3-5-20(19)27-21/h2-9,17H,10-14H2,1H3,(H,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	25
Johnson & Johnson Pharmaceutical					Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,...				J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX
					More data for this Ligand-Target Pair