BDBM242554 US9422240, 1-296
SMILES: OC(=O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(cc3)C3CC3)nc2)C1=O
InChI Key: InChIKey=FRLBQNHFDRCBNF-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Egl nine homolog 1 (Homo sapiens (Human)) | BDBM242554 (US9422240, 1-296) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | 7.5 | n/a |
TAISHO PHARMACEUTICAL CO., LTD US Patent | Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ... | US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K | |||||||||||
More data for this Ligand-Target Pair |