BDBM24268 Modified amino acid analog, 8c::methyl (2S)-2-amino-4-{[3-(benzyloxy)phenyl]carbamoyl}butanoate

SMILES: COC(=O)[C@@H](N)CCC(=O)Nc1cccc(OCc2ccccc2)c1

InChI Key: InChIKey=HKTDTEZFAUDEON-KRWDZBQOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24268   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A4 hydrolase (Homo sapiens (Human))	BDBM24268 (Modified amino acid analog, 8c | methyl (2S)-2-ami...) Show SMILES COC(=O)[C@@H](N)CCC(=O)Nc1cccc(OCc2ccccc2)c1 |r| Show InChI InChI=1S/C19H22N2O4/c1-24-19(23)17(20)10-11-18(22)21-15-8-5-9-16(12-15)25-13-14-6-3-2-4-7-14/h2-9,12,17H,10-11,13,20H2,1H3,(H,21,22)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair