BDBM243075 α-Gl inhibitor, C3

SMILES: Nc1ccc(cc1)S(=O)(=O)c1ccc(cc1)N1c2[nH]c(=O)[nH]c(=O)c2C(C(O)C(O)C(O)C(O)CO)c2c1[nH]c(=O)[nH]c2=O

InChI Key:

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 243075   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
alpha-glucosidase (Gaa) (Mus musculus (Mouse))	BDBM243075 (α-Gl inhibitor, C3) Show SMILES Nc1ccc(cc1)S(=O)(=O)c1ccc(cc1)N1c2[nH]c(=O)[nH]c(=O)c2C(C(O)C(O)C(O)C(O)CO)c2c1[nH]c(=O)[nH]c2=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
Shiraz University					Assay Description In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25°C with minor changes, according to the meth...				J Enzyme Inhib Med Chem 28: 1228-35 (2013) Article DOI: 10.3109/14756366.2012.727812 BindingDB Entry DOI: 10.7270/Q2XP73V0
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL12 (Saccharomyces cerevisiae)	BDBM243075 (α-Gl inhibitor, C3) Show SMILES Nc1ccc(cc1)S(=O)(=O)c1ccc(cc1)N1c2[nH]c(=O)[nH]c(=O)c2C(C(O)C(O)C(O)C(O)CO)c2c1[nH]c(=O)[nH]c2=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
Shiraz University					Assay Description In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25°C with minor changes, according to the meth...				J Enzyme Inhib Med Chem 28: 1228-35 (2013) Article DOI: 10.3109/14756366.2012.727812 BindingDB Entry DOI: 10.7270/Q2XP73V0
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL12 (Saccharomyces cerevisiae)	BDBM243075 (α-Gl inhibitor, C3) Show SMILES Nc1ccc(cc1)S(=O)(=O)c1ccc(cc1)N1c2[nH]c(=O)[nH]c(=O)c2C(C(O)C(O)C(O)C(O)CO)c2c1[nH]c(=O)[nH]c2=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	7.0	n/a
Shiraz University					Assay Description In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25°C with minor changes, according to the meth...				J Enzyme Inhib Med Chem 28: 1228-35 (2013) Article DOI: 10.3109/14756366.2012.727812 BindingDB Entry DOI: 10.7270/Q2XP73V0
					More data for this Ligand-Target Pair
alpha-glucosidase (Gaa) (Mus musculus (Mouse))	BDBM243075 (α-Gl inhibitor, C3) Show SMILES Nc1ccc(cc1)S(=O)(=O)c1ccc(cc1)N1c2[nH]c(=O)[nH]c(=O)c2C(C(O)C(O)C(O)C(O)CO)c2c1[nH]c(=O)[nH]c2=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.41E+4	n/a	n/a	n/a	n/a	7.0	n/a
Shiraz University					Assay Description In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25°C with minor changes, according to the meth...				J Enzyme Inhib Med Chem 28: 1228-35 (2013) Article DOI: 10.3109/14756366.2012.727812 BindingDB Entry DOI: 10.7270/Q2XP73V0
					More data for this Ligand-Target Pair