BDBM243334 US10053454, Example 78::US10196387, Example 78

SMILES: Cc1noc(C)c1-c1cc(C(N)=O)c2n(CC3CC3)c3ccc(cc3c2c1)S(C)(=O)=O

InChI Key: InChIKey=LCEJWNKDKMSXGH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 243334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM243334 (US10053454, Example 78 | US10196387, Example 78) Show SMILES Cc1noc(C)c1-c1cc(C(N)=O)c2n(CC3CC3)c3ccc(cc3c2c1)S(C)(=O)=O Show InChI InChI=1S/C23H23N3O4S/c1-12-21(13(2)30-25-12)15-8-18-17-10-16(31(3,28)29)6-7-20(17)26(11-14-4-5-14)22(18)19(9-15)23(24)27/h6-10,14H,4-5,11H2,1-3H3,(H2,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10053454 (2018) BindingDB Entry DOI: 10.7270/Q2C24ZFN
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM243334 (US10053454, Example 78 | US10196387, Example 78) Show SMILES Cc1noc(C)c1-c1cc(C(N)=O)c2n(CC3CC3)c3ccc(cc3c2c1)S(C)(=O)=O Show InChI InChI=1S/C23H23N3O4S/c1-12-21(13(2)30-25-12)15-8-18-17-10-16(31(3,28)29)6-7-20(17)26(11-14-4-5-14)22(18)19(9-15)23(24)27/h6-10,14H,4-5,11H2,1-3H3,(H2,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10196387 (2019) BindingDB Entry DOI: 10.7270/Q29S1T30
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM243334 (US10053454, Example 78 | US10196387, Example 78) Show SMILES Cc1noc(C)c1-c1cc(C(N)=O)c2n(CC3CC3)c3ccc(cc3c2c1)S(C)(=O)=O Show InChI InChI=1S/C23H23N3O4S/c1-12-21(13(2)30-25-12)15-8-18-17-10-16(31(3,28)29)6-7-20(17)26(11-14-4-5-14)22(18)19(9-15)23(24)27/h6-10,14H,4-5,11H2,1-3H3,(H2,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10196387 (2019) BindingDB Entry DOI: 10.7270/Q26112DD
					More data for this Ligand-Target Pair