BDBM243780 US9428456, 1.209

SMILES: Clc1cncc(c1)C(=O)Nc1cccc(CN2CCC(CC2)C(=O)NC2CCCC2)c1

InChI Key: InChIKey=RJUGTNWWOVEOEY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 7 (CXCR7) (Homo sapiens (Human))	BDBM243780 (US9428456, 1.209) Show SMILES Clc1cncc(c1)C(=O)Nc1cccc(CN2CCC(CC2)C(=O)NC2CCCC2)c1 Show InChI InChI=1S/C24H29ClN4O2/c25-20-13-19(14-26-15-20)24(31)28-22-7-3-4-17(12-22)16-29-10-8-18(9-11-29)23(30)27-21-5-1-2-6-21/h3-4,7,12-15,18,21H,1-2,5-6,8-11,16H2,(H,27,30)(H,28,31)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD US Patent					Assay Description CHO-K1 CXCR7 b-arrestin cells are detached from culture dishes with a cell dissociation buffer (Invitrogen, #13151-014) and collected in growing medi...				US Patent US9428456 (2016) BindingDB Entry DOI: 10.7270/Q29022PZ
					More data for this Ligand-Target Pair