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SMILES: Cc1cc(Nc2ccc3c(c2)oc(C)cc3=O)n2ncnc2n1

InChI Key: InChIKey=LVJXULJLNCBDTN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24410   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Plasmodium falciparum (isolate 3D7))		BDBM24410
PNG
(2-methyl-7-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimi...)
Show SMILES Cc1cc(Nc2ccc3c(c2)oc(C)cc3=O)n2ncnc2n1
Show InChI InChI=1S/C16H13N5O2/c1-9-5-15(21-16(19-9)17-8-18-21)20-11-3-4-12-13(22)6-10(2)23-14(12)7-11/h3-8,20H,1-2H3
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MMDB

KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.00E+3n/an/an/an/a8.020



University of Texas Southwestern Medical Center at Dallas



Assay Description
The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...

J Med Chem 51: 3649-53 (2008)


Article DOI: 10.1021/jm8001026
BindingDB Entry DOI: 10.7270/Q2PV6HNF
More data for this
Ligand-Target Pair