BDBM24414 (3R,5R)-7-[4-(benzylcarbamoyl)-2-(4-fluorophenyl)-5-(propan-2-yl)-1H-imidazol-1-yl]-3,5-dihydroxyheptanoic acid::Imidazole Series 1 Compound, 1

SMILES: CC(C)c1c(nc(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(O)=O)C(=O)NCc1ccccc1

InChI Key: InChIKey=ATGOOVTXNDYCBK-FGZHOGPDSA-N

Data: 1 ITC

PDB links: 1 PDB ID matches this monomer. 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 24414

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA) (Homo sapiens (Human))	BDBM24414 ((3R,5R)-7-[4-(benzylcarbamoyl)-2-(4-fluorophenyl)-...)	GoogleScholar PDB	KEGG MMDB PC cid PC sid PDB		-10.9	6.69	-17.7	7.87	7.20	30
Pfizer Inc.					J Med Chem 51: 3804-13 (2008)