BDBM244148 US9428492, 18

SMILES: C[C@H](O)c1nc(C)nn1-c1cc(nc(n1)C1CC1)C1C[C@H]1c1nc2ccccc2n1C

InChI Key: InChIKey=FWBGZQFVRXWFBV-ZDKIRESNSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 244148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM244148 (US9428492, 18) Show SMILES C[C@H](O)c1nc(C)nn1-c1cc(nc(n1)C1CC1)C1C[C@H]1c1nc2ccccc2n1C |r| Show InChI InChI=1S/C23H25N7O/c1-12(31)22-24-13(2)28-30(22)20-11-18(25-21(27-20)14-8-9-14)15-10-16(15)23-26-17-6-4-5-7-19(17)29(23)3/h4-7,11-12,14-16,31H,8-10H2,1-3H3/t12-,15?,16+/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.360	-12.9	n/a	n/a	n/a	n/a	n/a	7.2	25
Merck Sharp & Dohme Corp. US Patent					Assay Description The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...				US Patent US9428492 (2016) BindingDB Entry DOI: 10.7270/Q2HD7TKM
					More data for this Ligand-Target Pair