BDBM24421 (3R,5R)-7-[2-(benzylcarbamoyl)-4-(4-fluorophenyl)-1-(propan-2-yl)-1H-imidazol-5-yl]-3,5-dihydroxyheptanoic acid::Imidazole Series 2 Compound, 8

SMILES: CC(C)n1c(CC[C@@H](O)C[C@@H](O)CC(O)=O)c(nc1C(=O)NCc1ccccc1)-c1ccc(F)cc1

InChI Key: InChIKey=XRFGQWQHNSTQDR-FGZHOGPDSA-N

Data: 1 ITC

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 24421

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA) (Homo sapiens (Human))	BDBM24421 ((3R,5R)-7-[2-(benzylcarbamoyl)-4-(4-fluorophenyl)-...)	GoogleScholar PDB	KEGG PC cid PC sid		-10.4	5.99	-16.4	7.50	7.20	30
Pfizer Inc.					J Med Chem 51: 3804-13 (2008)