BDBM24430 (3R,5R)-7-(5-{[4-(dimethylcarbamoyl)phenyl]carbamoyl}-3,4-bis(4-fluorophenyl)-1-methyl-1H-pyrrol-2-yl)-3,5-dihydroxyheptanoic acid::Pyrrole Series 5 Compound, 17
SMILES: CN(C)C(=O)c1ccc(NC(=O)c2c(c(c(CC[C@@H](O)C[C@@H](O)CC(O)=O)n2C)-c2ccc(F)cc2)-c2ccc(F)cc2)cc1
InChI Key: InChIKey=XZALSZSWTBSRFN-KAYWLYCHSA-N
Data: 1 ITC
Cell (A) | Syringe (B) | Cell Links | Syringe Links | Cell + Syr Links | ΔG° kcal/mole | -TΔS° kcal/mole | ΔH° kcal/mole | log K | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA) (Homo sapiens (Human)) | BDBM24430 ((3R,5R)-7-(5-{[4-(dimethylcarbamoyl)phenyl]carbamo...) | GoogleScholar PDB | KEGG PC cid PC sid | -11.5 | 1.60 | -13.1 | 8.27 | 7.20 | 30 | |
Pfizer Inc. | J Med Chem 51: 3804-13 (2008) |